Cocaine and Ketamine are both powerful drugs that have separate attributes and effects. Cocaine stimulates are comparable to increasing dopamine levels in the brain, which leads feeling of euphoria and increased energy, while Ketamine works by blocking receptors, leading to a dissociative state and hallucinations. Both drugs have high potential for side effects, which directly affect the user’s brain. It is crucial to be aware of the risks associated with Ketamine vs Cocaine use, and also important for drug addiction therapy.